• The Best Clinic
    2017
  • The Best Clinic
    2018

    Hyperthermic intraperitoneal chemotherapy (HIPEC)

    Hyperthermic chemotherapy is one of the important steps in the fight against cancer. Some types of cancer and their stages cannot be treated with traditional intravenous chemotherapy, and the desired result cannot be achieved. Despite chemotherapy, the disease progresses, and the patient’s life worsens faster than expected. It is in these areas that hyperthermal intraperitoneal chemotherapy is used.

    The leading Israeli clinic Tel Aviv Medical Clinic employs real professionals who have been involved in the detection and treatment of various pathologies for over 10 years. We use the latest equipment and innovative methods of therapy. This therapy is most often used to treat ovarian cancer in women. Also, it is used for cancer of the colon, stomach, appendix and cancers of the peritoneum. In recent years, it has also been used in pancreatic cancer.

    When hyperthermic chemotherapy is used

    Many types of cancers arising from the abdominal organs can also affect the abdominal membrane, called the “peritoneum”. The peritoneum is a tissue that facilitates the friction of organs, secreting a small amount of fluid that covers both the inside of the abdominal wall and the surface of the organs. In cancers originating from the intraperitoneal organs, cancer cells include peritoneum in the vicinity or during secretion. This usually indicates that cancer has reached its final stage. In cancers associated with the peritoneum, intravenous chemotherapy is ineffective because the drugs cannot fully reach the peritoneum.

    The basic principle of treating abdominal cancer is to consider the peritoneum as an organ and to remove the affected peritoneum and affected organs using cytoreductive surgery. Intraperitoneal chemotherapy is performed after this operation, i.e. after removal of all tumour tissue to destroy residual microscopic metastases.

    Advantages of the procedure 

    • Heat increases the destructive effect of the selected chemotherapeutic agent on cancer cells. 
    • Intraperitoneal chemotherapy is distributed in the abdominal cavity through manual manipulation; heat promotes uniform distribution of the drug to all surfaces within the abdomen.
    • During HIPEC, the adverse effect of the drug on kidney function and urine output can be monitored and adequate measures are taken. 
    • Many physiological parameters of the patient (body temperature, coagulation, hemodynamics, etc.) can be normalized during HIPEC. 
    • During HIPEC, tumour cells are mechanically eliminated from the surface of the small intestine and layers of fibrin clots.

       

     

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