Chronic Myelodic Leukemia (CML)

A feature of chronic myeloid leukemia is the excessive formation of cells such as granulocytes in the bone marrow. The constituents of leukocytes and their precursors accumulate abnormally in the blood. Myeloid cells of the hematopoietic system are involved in the pathological process. The disease is characterized by slow progress and the absence of a special chromosomal rearrangement in the composition of leukemic cells.

The effect of therapy will be much higher if the disease is diagnosed at an early stage, has not yet given serious complications by penetration into other organs. An important role is played by 100% accuracy of the diagnosis, on which the tactics of the developed treatment depend, and as a result, the health and life of the patient. At Tel Aviv Medical Clinic, patients are examined according to a complex scheme that excludes errors.

The specialists of the Department of Hematology have considerable experience in the fight against blood oncological diseases, they are constantly improving the technique of diagnosis and therapy to make the treatment even better. Our doctors value their reputation; for each patient, they select an individual, most optimal treatment regimen.

Symptoms of the disease

CML in the initial stages is not accompanied by pronounced symptoms, and gradually from the latent phase passes into the crisis stage, accompanied by a whole bunch of complications. This type of chronic leukemia occurs at any age, equally among both sexes, and rarely affects children. The following symptoms are a cause for concern:

• Rapid fatigue and unexplained weakness; 
• Decrease in body weight in the absence of appetite; 
• Fever; 
• Feeling of heaviness in the abdomen; 
• Night sweat; 
• Pathological enlargement of the spleen; 
• Bleeding, bruising; 
• Skin rash; 
• Pale skin; 
• Shortness of breath.

The accumulation of blast cells can lead to bone and joint pain. A qualified specialist will carry out the necessary diagnostics and select the optimal therapy regimen.

Treatment

In the clinic, a consultation of specialists deals with the determination of treatment tactics for each patient. This makes it possible to take into account all the nuances of the disease and prescribe the most effective treatment, taking into account the patient’s age, general health, stage of the disease. When prescribing treatment, doctors are guided by the recommendations of international medical protocols. Conservative therapy is often used as a treatment. If it is ineffective, the doctor will decide on a bone marrow transplant.