Desmoplastic Small Round Cell Tumors (DSRCT) Diagnosis

Today, foreign oncologists use ultra-modern approaches to determine the type of soft tissue sarcoma in children. The effectiveness of the treatment of the disease largely depends on this. Thanks to this approach, many clinics today help to restore health to children. The presence of some diseases and hereditary disorders increases the risk of the child developing soft tissue sarcoma. That is why when planning the treatment of bone sarcoma in Israel, doctors study the presence of factors that can provoke the development of the disease. Risk factors include anything that can affect the appearance of the disease. Having a risk factor does not mean getting cancer, but if there are any, you need to inform the attending physician.

Symptoms of the disease

Desmoplastic small cell tumour is a rare disease affecting predominantly young adults and male children. Usually, a tumour occurs in the abdominal (more often) or thoracic cavity, affects the omega, gastrointestinal tract, bladder and other organs and systems. It is distinguished from other small round cell tumors by characteristic histology – a cluster of blue small round or ovoid cells in a desmoplastic stroma, which is differentiated by epithelial, mesenchymal, myogenic, neural mitosis.

The most common symptoms are abdominal pain, bloating, a sense of severity and hepatomegaly. Less common signs are retroperitoneal lymphadenopathy, hydronephrosis, bulobestruction, calcification and thickening of the nodal peritoneal lymph nodes. These symptoms are not typical and do not serve as a basis for diagnosis. Therefore, it is important to consider DSRCT as a possible diagnosis when a young person has nonspecific abdominal symptoms and there are radiological signs of disseminated intraperitoneal malignancy.

Diagnosis of the disease

If cancer is suspected, parents take their children to the Israeli Tel Aviv Medical Clinic, where there is the necessary advanced equipment. We use innovative examination techniques and unique, child-friendly treatment methods.

The examination of the child is carried out by specialists of related profiles, which helps to draw up an optimal treatment plan, taking into account the degree of prevalence, nature and structure of the tumour. The Department of Pediatric Oncology uses:

• CT;
• MRI;
• Radiography;
• Scintigraphy;
• PET;
• Taking biopsies and blood for laboratory examination.

Based on the obtained data, the doctor selects an individual therapy scheme taking into account the features of the development of pathology and the general state of the patient.