Hodgkin Lymphoma Treatment

Hodgkin’s lymphoma is a type of lymphoma characterized by the presence of a special type of malignant cells called Reed-Sternberg cells. Why the disease occurs, experts cannot say. The disease is characterized primarily by a tumor lesion of the lymph nodes with a gradual spread of the disease from one group of lymph nodes to another. Other organs can also be affected, primarily the spleen, as well as the liver, lungs, intestines, bone marrow, etc. A distinctive feature of LGM in comparison with other lymphomas is the presence in the affected lymph nodes of a special type of cells called Berezovsky-Sternberg-Reed cells. These are giant cells derived from B lymphocytes.

Treatment of the disease

Each patient receives an individual treatment plan, which takes into account his age, possible chronic diseases, stage of the disease, degree of malignancy, and the presence of contraindications. Tel Aviv Medical Clinic specialists use innovative approaches in the treatment of blood cancer. With the help of the latest equipment, it is possible to identify pathology at the initial stage and successfully cure it. Our qualified doctors use a comprehensive approach to cancer treatment, which includes chemotherapy, surgery, and drug treatment.

Treatment of pathology is based on a combination of chemotherapy and radiation. The choice of a specific therapy depends on the variant of the disease, the patient’s age, stage (local or widespread damage to the body), concomitant diseases and other factors.

Chemotherapy with high doses of chemotherapy drugs is often used. The duration of treatment is 2-5 months. Doctors use ABVD courses (adriablastin, bleomycin, vinblastine, dacarbazine), BEACOPP (bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, prednisone) and other chemotherapy courses, the amount of which is determined depending on the stage of the disease.

Chemotherapy is followed by radiation therapy. The dose of radiation is determined by the oncohematologist depending on the stage of the disease, the protocol used and the organ to be irradiated. In difficult cases (resistance of the disease to therapy, relapses), high-dose therapy with autologous bone marrow transplantation can be used. Allogeneic transplantation is rarely used.