Chemotherapy in Israel remains one of the key treatment methods for cancer. However, modern oncology has changed significantly. Today, chemotherapy is rarely used as the only treatment. In most cases, it is combined with immunotherapy, targeted therapy, surgery, and radiation therapy.
In clinical practice, the decision to use chemotherapy is made individually. Doctors consider the type of tumor, stage of disease, molecular characteristics, patient age, and overall health. In some cases, chemotherapy remains the main treatment. In others, it becomes part of a combined approach.
Chemotherapy Specialists
Selecting a chemotherapy regimen requires experience in systemic cancer treatment and understanding modern combination therapy options. Consultations are provided by oncologists specializing in different cancer fields.
Chemotherapy consultations are provided by:
Prof. Tamar Safra — Gynecologic Oncology
Dr. Roman Meirovitz — Lung and Gastrointestinal Oncology
Dr. Irina Stefansky — Systemic Oncology and Chemotherapy
Dr. Daniel Kaizman — Urologic Oncology
Dr. Felix Bukstein — Neuro-Oncology
Specialists review medical documentation, staging, and molecular characteristics to select the most appropriate treatment strategy.




















Role of Chemotherapy in Modern Oncology
Chemotherapy may be used in several clinical situations:
- As primary treatment
- Before surgery to reduce tumor size
- After surgery to reduce recurrence risk
- In metastatic disease to control progression
- In combination with immunotherapy or targeted therapy
In some cases, chemotherapy enhances the effectiveness of other treatments. In others, it helps stabilize disease.
Where Chemotherapy is Used
Chemotherapy is used in many cancer types. However, treatment approaches vary depending on tumor type.
Hematologic Oncology
Chemotherapy remains one of the main treatments for:
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Multiple myeloma
- Myelodysplastic syndromes
In some cases, chemotherapy is combined with immunotherapy, targeted therapy, or bone marrow transplantation.
Solid Tumors
Chemotherapy is widely used in:
- Lung cancer
- Breast cancer
- Colorectal cancer
- Gastric cancer
- Pancreatic cancer
- Liver cancer
Gynecologic Oncology
Chemotherapy is used for:
Urologic Oncology
Chemotherapy may be used for:
Neuro-Oncology
Chemotherapy is used in:
Types of Chemotherapy
Neoadjuvant Chemotherapy
Used before surgery to shrink tumors.
Commonly used in:
- Breast cancer
- Lung cancer
- Rectal cancer
- Gastric cancer
Examples:
- AC
- AC-T
- FOLFOX
- Carboplatin + Paclitaxel
Adjuvant Chemotherapy
Used after surgery to reduce recurrence risk.
Examples:
- FOLFOX
- CAPOX
- AC-T
- CMF
Induction Chemotherapy
Used as primary treatment.
Examples:
- CHOP
- R-CHOP
- BEP
Palliative Chemotherapy
Used in advanced cancer to control disease.
Examples:
- FOLFIRI
- FOLFOX
- Gemcitabine
- Paclitaxel
Maintenance Chemotherapy
Used after disease control.
Examples:
- Pemetrexed
- Capecitabine
- Gemcitabine
Chemotherapy in Combination with Modern Treatments
Chemotherapy and Immunotherapy
Used in:
- Lung cancer
- Melanoma
- Kidney cancer
- Bladder cancer
Chemotherapy and Targeted Therapy
Used in:
- Breast cancer
- Lung cancer
- Colorectal cancer
Chemotherapy and Clinical Trials
Clinical trials play an important role in modern oncology. These may include:
- New chemotherapy drugs
- New combinations
- Personalized treatment approaches
How Chemotherapy is Given
Chemotherapy may be administered:
- Intravenously
- Orally
- Subcutaneously
- Intra-arterially
- Intrathecally
Possible Side Effects
- Fatigue
- Nausea
- Low blood counts
- Hair loss
- Reduced immunity
Modern supportive treatments help control most side effects.
Personalized Treatment Approach
Modern oncology increasingly relies on personalized treatment:
- Molecular characteristics
- Genetic mutations
- Patient condition
- Previous treatments
Oncology Consultation by Cancer Type
An oncology consultation may be useful when:
- New diagnosis
- Treatment selection
- Considering chemotherapy
- Second opinion
- Clinical trials
- Disease progression
Oncology Consultation in Israel
If you have a diagnosis or suspected cancer, you can request a consultation.
Leave your details and our team will contact you to schedule a consultation with an oncologist specializing in your cancer type.
📞 Phone: +972-73-374-6844
💬 WhatsApp: +972-52-337-3108
📧 Email: [email protected]
Frequently Asked Questions About Chemotherapy
Answered by Dr. Irina Stefansky, Medical Oncologist
1. Do all patients need chemotherapy?
No, not at all. And actually, this is one of the most common fears I hear. People hear the diagnosis and immediately think chemotherapy is inevitable.
But in reality, it’s much more nuanced. Sometimes we don’t recommend chemotherapy at all. In some cases, targeted therapy is a better option, sometimes immunotherapy, and occasionally we even start with observation.
I always tell my patients — first we need to understand the tumor type, stage, test results, and molecular markers. Only after that do we decide on treatment.
So no, chemotherapy is not for everyone. And it’s definitely not always the first option.
2. How difficult is chemotherapy to tolerate?
This is probably the number one concern for most patients. Many people still think about chemotherapy the way it was 20 years ago — severe side effects, hospitalizations, feeling very sick.
But things have changed significantly. The drugs are different now, and we have much better supportive treatments.
In practice, many of my patients continue working and maintaining their daily routines. Of course, everyone is different, and side effects can occur. But in many cases, chemotherapy is much easier than patients expect.
Sometimes the fear of chemotherapy is actually harder than the treatment itself.
3. When is chemotherapy really necessary?
There are several situations. Sometimes we recommend chemotherapy before surgery, to shrink the tumor. That’s quite common.
Other times, we recommend it after surgery to reduce the risk of recurrence.
And sometimes chemotherapy is used in advanced disease, when our goal is to control the cancer and slow its progression.
We also often combine chemotherapy with immunotherapy or targeted therapy. In some cases, this combination can be very effective.
So it really depends on the situation. There’s no single answer that fits everyone.
4. Can I get a second opinion before starting chemotherapy?
Yes, of course. I’m always comfortable with that. In fact, sometimes I recommend it myself.
Chemotherapy in Israel is an important step, and patients should understand why a specific treatment is being recommended and what other options exist.
During a consultation, we review medical records, test results, and sometimes suggest alternative approaches. In some cases, there may be newer therapies or clinical trial options available.
Getting a second opinion is completely normal. It doesn’t mean someone made a mistake. Sometimes there are simply several valid treatment options.
5. How do you decide which chemotherapy regimen is right for me?
In oncology, treatment is usually evaluated after 3–4 cycles, which typically takes about 2–3 months.
Patients often ask me to check earlier, but it’s important to understand that many drugs have a cumulative effect, and evaluating too early may not give accurate results.
Only in certain situations, for example if symptoms worsen, we may recommend earlier imaging or testing.
Every treatment plan is personalized, and decisions are always based on how the patient responds.
6. Can treatment start after an online consultation?
Yes, in many cases it can. Especially for patients coming from other countries.
Usually, patients send their medical records first — reports, imaging, pathology results. I review everything before the consultation, and then we discuss possible treatment options.
After that, we decide on the next steps. Some patients come to Israel for treatment, while others continue treatment in their home country with our recommendations.
A remote consultation is often the first and very helpful step. It allows patients to understand whether they are on the right path without needing to travel immediately.
7. Can patients from other countries request a consultation?
Yes, absolutely. And actually, many of my patients come from abroad.
Often patients are looking for a second opinion, clarification of treatment options, or access to advanced therapies available in Israel.
Patients send their documents in advance. Our international medical team organizes the information so that the clinical picture is clear. If something is missing, I request additional information.
We then schedule the consultation, usually via Zoom or WhatsApp video. After the consultation, the patient receives a structured treatment plan.
8. When should clinical trials be considered?
Clinical trials are not always a “last resort,” as many people think. Sometimes they are simply an opportunity to receive newer and more advanced treatment.
For example, clinical trials may include new medications, new combinations, or personalized treatment approaches. In some cases, these options can be very promising.
During the consultation, I evaluate whether a patient may be suitable for a clinical trial. Sometimes these options are available, sometimes not.
But it’s definitely worth discussing — especially in complex or advanced cases.
























